Parkinson’s Disease Case 3

A 70-year-old male with a 20-year history of Parkinson’s disease, diagnosed at age 50, has been managed with Carbidopa 5mg PO daily and underwent deep brain stimulation (DBS) surgery 8 years ago, with a subcutaneous battery implanted in the right upper pectoral region. Since surgery, his symptoms have remained generally stable, though he continues to experience emotional dysregulation, such as inappropriate affective responses (weepy during happy events, cheerful during sad ones). His past medical history is also significant for fatty liver disease.

In August 2025, he underwent IV stem cell therapy with umbilical cord–derived stem cells (60 million non-expanded, pure-form cells) combined with exosomes. The treatment was well tolerated.

Following therapy, the patient reported immediate and progressive improvements. On the day of treatment, he was able to rise from a chair unassisted and walked two and a half blocks from the clinic to his hotel. Within a week, he noted sharper vision and improved focus, particularly from an old injury, along with a stronger and clearer voice. He also regained a sense of smell that had been absent for several years. Family and friends observed that his face appeared more vibrant and youthful. Most notably, after years of struggling with ambulation, he now walks with greater confidence and no longer relies on a walker.